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A Research Institute

As a renowned African institute in a world class African University, Wits RHI addresses some of the greatest public health concerns affecting our region, including HIV and its related problems, sexual and reproductive health and vaccinology.

Wits RHI is the largest research institute affiliated with the Faculty of Health Sciences at the University of the Witwatersrand.

The institute was established by Prof Helen Rees in 1994 to assist the new South African government to formulate and implement new national policies around sexual and reproductive health. It has shaped itself as an African institute leading multidisciplinary research, focusing mainly on HIV, sexual reproductive health (SRH), and vaccine-preventable diseases (VPDs). Recently, Wits RHI expanded its portfolio to include COVID-19 and other respiratory pathogens, emerging global health crises (including antimicrobial resistance), and climate change and health.

Its research studies are carried out in collaboration with multiple partners within and outside the African region. 

Wits RHI in Numbers

Staff Members
3000+
Research and Implementation Sites
50
Current Active Grants
93
Academic Joint Appointments
51
Provides technological support to national, regional, and global committees (2022)
162
Published academic journals and book chapters (2023)
118

Latest Projects And News

Projects

Jansen ENSEMBLE VAC31518COV3001 HG

A Randomized , Double -Blinded, Placebo-Controlled Phase 3 Study to assess the Efficacy and safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older. Rationele The development of a vaccine for Coronavirus disease -19 (COVID-19) will be critical for containing the current outbreak and preventing future outbreaks, as no vaccine is currently available. Janssen is developing a vaccine for the prevention of SARS-CoV-2-mediated COVID-19 in adults. In this study efficacy, safety and Immunogenicity will be evaluated in adults living in or going to locations with high risk of SARS-CoV-2 infection after vaccine administration. Primary Objectives To demonstrate the efficacy of AD26.COV2.S in the prevention of molecularly confirmed moderate to severe/critical COVID-19, as compared to Placebo, in SARS-CoV-2 Seronegative adults. Study Population Adults 18 Years and Older Investigators Dr Faeezah Patel, Principal Investigator Dr Elizea Horne, Co-Principal Investigator Dr Lee Fairlie, Sub Investigator Dr Masebole…

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Projects

Jansen ENSEMBLE VAC31518COV3001 HG

A Randomized , Double -Blinded, Placebo-Controlled Phase 3 Study to assess the Efficacy and safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older.…

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Projects

South African Population Research Infrastructure Network (SAPRIN)

South African Population Research Infrastructure Network (SAPRIN): A GRT-INSPIRED Sub Study of COVID-19 Perceptions, Impacts and Seroprevalence Among Residents of Atteridgeville, Melusi and Hillbrow in Gauteng, South Africa Rationale The…

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Projects

The HIV Prevention Trials Network

The ECHO Study is designed to assess three highly effective, reversible long-acting contraceptive methods: the progestogen-only contraceptive depot medroxyprogesterone acetate (DMPA), the Jadelle sub-dermal implant and the copper intrauterine device…

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Projects

ECHO Study

The ECHO Study is designed to assess three highly effective, reversible long-acting contraceptive methods: the progestogen-only contraceptive depot medroxyprogesterone acetate (DMPA), the Jadelle sub-dermal implant and the copper intrauterine device…

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Latest News From Around The World Of Wits RHI

Chimoyi, L., N. Tshuma, K. Muloongo, G. Setswe, B. Sarfo and P. S. Nyasulu (2015)

Kavanagh, M. M., J. Cohn, L. Mabote, B. M. Meier, B. Williams, A. Russell, K. Sikwese and B. K. Baker (2015) 

Haberer, J. E., D. R. Bangsberg, J. M. Baeten, K. Curran, F. Koechlin, K. R. Amico, P. Anderson, N. Mugo, F. Venter and P. Goicochea (2015)

Our Researchers

Our Donors and Partners

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