Safer Conception

Safer Conception

Safer Conception

An assessment of the feasibility, acceptability and effectiveness of integrating Safer Conception Service delivery models into Primary Healthcare Facilities: An Implementation Science Project

Pregnancy rates (including planned and unplanned pregnancies) in HIV-affected couples – even before the advent of ART – are often as high as that seen in the general population. Clearly, having a child/children remains a priority for a large proportion of HIV-infected people. However, sero-discordant couples, where one partner is HIV positive and the other HIV negative, remain prevalent with up to 47% of HIV positive women and men having an HIV negative partner. Despite the risk of horizontal transmission within these partnerships, many HIV sero-discordant couples prefer natural conception methods (unprotected sex) or cannot afford assisted reproduction technologies. Therefore, an increasingly important aspect of both chronic disease management and prevention efforts involves supporting those who wish to conceive to do so as safely as possible, yet this aspect of care often remains unaddressed. There is limited evidence of feasibility and acceptability of these options in public sector settings let alone the success of scaling such programme. This study will therefore provide information on the feasibility and potential uptake of these approaches which have been expanded from the demonstration project.

Nine Primary Health Care facilities in the inner city of Johannesburg

Any woman aged 18-49 years and any man aged 18-59 years in a sexually active HIV-affected partnership (seroconcordant, discordant or one partner of unknown status), who desires to become pregnant and is willing to consider options for conceiving safely, and who is eligible to give consent to take part in the study.

Dr. Natasha Davies; Dr. Saiqa Mullick, Diantha Pillay, Nicolette Naidoo


Dr Sheree Schwartz, Johns Hopkins University